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 Cancer can cause endocrine and metabolic complications due to;

  • the direct effect of the primary tumour or its metastases interfering with function by infiltration or obstruction


  • by the release of products such as hormones,cytokines and growth factors by tumour cells or normal cells as a response to the presence of the tumour 


  • Hypomagnesaemia is an electrolyte imbalance and is indicated by a low level of magnesium in the blood.  The normal adult value for magnesium is 1.5-2.5 mEq/L. Normal levels of magnesium are important for the maintenance of heart and nervous system function.

  • Hypomagnesaemia - UKONS initial management 

  • Hypomagnesemia in the Cancer Patient- Biruh T. Workeneh, Nupur N. Uppal, Kenar D. Jhaveri and Helbert Rondon-Berrios- Hypomagnesemia is a common medical problem that contributes to the morbidity and mortality of patients with cancer.

  • Acute hypocalcaemia can be life threatening, necessitating urgent treatment. In severe cases, intravenous calcium forms the mainstay of initial therapy, but it is essential to ascertain the underlying cause and commence specific therapy as early as possible

  • Emergency management of acute hypocalcaemia in adult patients:SOCIETY FOR ENDOCRINOLOGY ENDOCRINE EMERGENCY GUIDANCE. 


 Useful link -  The Society for Endocrinology  

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